Causes of Gynecomastia

So What are the Possible Causes of gynecomastia?

  • Persistent pubertal gynecomastia – 25%

  • Drugs – 10-25%

  • No detectable abnormality – 25%

  • Cirrhosis or malnutrition – 8%

  • Primary hypogonadism – 8%

  • Testicular tumors – 3%

  • Secondary hypogonadism – 2%

  • Hyperthyroidism - 1.5%

  • Chronic renal insufficiency – 1%

Emmanuel De La Cruz M.D.

References:

Braunstein GD. Gynecomastia. N Engl J Med. Feb 18 1993;328(7):490-5

Mahoney CP. Adolescent gynecomastia. Differential diagnosis and management. Pediatr Clin North Am. Dec 1990;37(6):1389-404

Carlson HE. Approach to the patient with gynecomastia. J Clin Endocrinol Metab. Jan 2011;96(1):15-21

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